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Resins for Oligonucleotide Synthesis

  • 商品品牌:Rapp-polymere 德国
  • 商品重量:
  • 商品规格:
  • 上架时间:2020-04-08
  • 产品描述:B6 Resins for Oligonucleotide Synthesis TentaGel N Resins B6.1 base TentaGel N Resins 货号 名称 particle size capacity 包装 N 30 000 TentaGel N OH 90 m 200 - 250 mol/g 1g N 30 000 TentaGel N OH 90 m 200 - 250 mol/g 5g N 30 000 TentaGe

B6 Resins for Oligonucleotide Synthesis

B6.1 Base TentaGel® N Resins

货号 名称 particle size capacity 包装
N 30 000 TentaGel® N OH 90 µm 200 - 250 µmol/g 1g
N 30 000 TentaGel® N OH 90 µm 200 - 250 µmol/g 5g
N 30 000 TentaGel® N OH 90 µm 200 - 250 µmol/g 25g
N 30 002 TentaGel® N NH? 90 µm 200 - 250 µmol/g 1g
N 30 002 TentaGel® N NH? 90 µm 200 - 250 µmol/g 5g
N 30 002 TentaGel® N NH? 90 µm 200 - 250 µmol/g 25g
B6.2 Preloaded TentaGel® N Resins
货号 名称 particle size capacity 包装
N 30 002-1 TentaGel® N A 90 µm 170 - 220 µmol/g 1g
N 30 002-1 TentaGel® N A 90 µm 170 - 220 µmol/g 5g
N 30 002-1 TentaGel® N A 90 µm 170 - 220 µmol/g 25g
N 30 002-2 TentaGel® N C 90 µm 170 - 220 µmol/g 1g
N 30 002-2 TentaGel® N C 90 µm 170 - 220 µmol/g 5g
N 30 002-2 TentaGel® N C 90 µm 170 - 220 µmol/g 25g
N 30 002-3 TentaGel® N G 90 µm 170 - 220 µmol/g 1g
N 30 002-3 TentaGel® N G 90 µm 170 - 220 µmol/g 5g
N 30 002-3 TentaGel® N G 90 µm 170 - 220 µmol/g 25g
N 30 002-4 TentaGel® N T 90 µm 170 - 220 µmol/g 1g
N 30 002-4 TentaGel® N T 90 µm 170 - 220 µmol/g 5g
N 30 002-4 TentaGel® N T 90 µm 170 - 220 µmol/g 25g

²B7 Resins with Linkers

B7.1 Bromo Acetal Resins

B7.1.1 HypoGel® Bromo Acetal Resins
HypoGel® is a hydrophilic gel type resin which combines high capacities with good solvent compatibility. Glycol spacers with n = 5 or 10 EO units separate the reactive sites from the polystyrene matrix and modify the hydrophobic properties of the polystyrene backbone. Due to the spacer effect the functional group shows a higher mobility which results in higher kinetic rates and high resolution NMR spectra from immobilized compounds on the bead. The resin is compatible to a wide range of solvents and in contrast to polystyrene even polar solvents like methanol or ethanol can be used.
These resins show high loading and a hydrophilicity between polystyrene and TentaGel®
Reaction with primary amines generates immobilized N-substituted glycinal acetals suitable for the synthesis of heterocycles derived from 1-acyl-3-oxopiperazine.
Literature
L 17
货号 名称 particle size capacity 包装
SP200 110150 190 HypoGel® 200 Bromo Acetal 110 - 150 µm 0.75 - 0.95 mmol/g 5g
SP200 110150 190 HypoGel® 200 Bromo Acetal 110 - 150 µm 0.75 - 0.95 mmol/g 25g
SP200 110150 190 HypoGel® 200 Bromo Acetal 110 - 150 µm 0.75 - 0.95 mmol/g 100g
SP400 110150 190 HypoGel® 400 Bromo Acetal 110 - 150 µm 0.6 - 0.8 mmol/g 5g
SP400 110150 190 HypoGel® 400 Bromo Acetal 110 - 150 µm 0.6 - 0.8 mmol/g 25g
SP400 110150 190 HypoGel® 400 Bromo Acetal 110 - 150 µm 0.6 - 0.8 mmol/g 100g
B7.1.2 TentaGel® Bromo Acetal Resins
TentaGel® resins are grafted copolymers consisting of a low crosslinked polystyrene matrix on which polyethylene glycol (PEG or POE) is grafted. The PEG spacer is attached to the matrix via an ethyl ether group which increases stability towards acid treatment and minimizes PEG-leaching. As PEG is a "chameleon type" polymer with hydrophobic and hydrophilic properties, the graft copolymer shows modified physico chemical properties which are highly dominated by the PEG moiety (and no longer by the polystyrene matrix). These graft copolymers are pressure stable and can be used in batch processes as well as under continuous flow conditions. The PEG spacer is in the range of MW 3000 Da.
Reaction with primary amines generates immobilized N-substituted glycinal acetals suitable for the synthesis of heterocycles derived from 1-acyl-3-oxopiperazine.
Literature
L 4, L 5, L 6, L 7, L 24, L 25, L 47; see also: General Information
货号 名称 particle size capacity 包装
HL 12 019 TentaGel® HL Bromo Acetal 75 µm 0.4 - 0.55 mmol/g 5g
HL 12 019 TentaGel® HL Bromo Acetal 75 µm 0.4 - 0.55 mmol/g 25g
HL 12 019 TentaGel® HL Bromo Acetal 75 µm 0.4 - 0.55 mmol/g 100g

B7.2 Diol Resins

B7.2.1 HypoGel® Diol Resins
货号 名称 particle size capacity 包装
SP200 110150 10 HypoGel® 200 Diol 110 - 150 µm 1.2 - 1.5 mmol/g 5g
SP200 110150 10 HypoGel® 200 Diol 110 - 150 µm 1.2 - 1.5 mmol/g 25g
SP200 110150 10 HypoGel® 200 Diol 110 - 150 µm 1.2 - 1.5 mmol/g 100g
SP400 110150 10 HypoGel® 400 Diol 110 - 150 µm 0.9 - 1.3 mmol/g 5g
SP400 110150 10 HypoGel® 400 Diol 110 - 150 µm 0.9 - 1.3 mmol/g 25g
SP400 110150 10 HypoGel® 400 Diol 110 - 150 µm 0.9 - 1.3 mmol/g 100g
B7.2.2 TentaGel® Diol Resins
货号 名称 particle size capacity 包装
HL 12 010 TentaGel® HL Diol 75 µm 0.6 - 0.8 mmol/g 5g
HL 12 010 TentaGel® HL Diol 75 µm 0.6 - 0.8 mmol/g 25g
HL 12 010 TentaGel® HL Diol 75 µm 0.6 - 0.8 mmol/g 100g

B7.3 p - Nitrophenyl Carbonate Resin

B7.3.1 p - Nitrophenyl Carbonate on TentaGel PHB Resin
TentaGel® resins are grafted copolymers consisting of a low crosslinked polystyrene matrix on which polyethylene glycol (PEG or POE) is grafted. The PEG spacer is attached to the matrix via an ethyl ether group which increases stability towards acid treatment and minimizes PEG-leaching. As PEG is a "chameleon type" polymer with hydrophobic and hydrophilic properties, the graft copolymer shows modified physico chemical properties which are highly dominated by the PEG moiety (and no longer by the polystyrene matrix). These graft copolymers are pressure stable and can be used in batch processes as well as under continuous flow conditions. The PEG spacer is in the range of MW 3000 Da.
Amines can be attached to the p-nitrophenyl carbonate resin to form the corresponding resin bound carbamates.
Literature
L 4, L 5, L 6, L 7, L 8, L 24, L 25, L 43, L 54; see also: General Information.
货号 名称 particle size capacity 包装
S 30 050 TentaGel® S – NPC 90 µm 0.2 - 0.3 mmol/g 1g
S 30 050 TentaGel® S – NPC 90 µm 0.2 - 0.3 mmol/g 5g
S 30 050 TentaGel® S - NPC 90 µm 0.2 - 0.3 mmol/g 25g
B7.3.2 p - Nitrophenyl Carbonate on Wang Resin
Amines can be attached to the p-nitrophenyl carbonate resin to form the corresponding resin bound carbamates. As an example the following compounds were synthesized by modifications on the resin bound carbamates: unsymetrical diamines, allylamines, guanidines, hydantoines, piperazines, triazolidienones, quinazoline diones ect.
货号 名称 particle size capacity 包装
H 100 50 Polystyrene Wang NPC 100 - 200 mesh 0.8 - 1.2 mmol/g 1g
H 100 50 Polystyrene Wang NPC 100 - 200 mesh 0.8 - 1.2 mmol/g 5g
H 100 50 Polystyrene Wang NPC 100 - 200 mesh 0.8 - 1.2 mmol/g 25g
H 400 50 Polystyrene Wang NPC 200 - 400 mesh 0.8 - 1.2 mmol/g 1g
H 400 50 Polystyrene Wang NPC 200 - 400 mesh 0.8 - 1.2 mmol/g 5g
H 400 50 Polystyrene Wang NPC 200 - 400 mesh 0.8 - 1.2 mmol/g 25g

B7.4 Polymer Bound Acrylic Ester (REM Resins)

These resins with the immobilized acrylic acid are supports for the SOPS of tertiary amines. The first step is a Michael addition of a primary or secondary amine followed by quarternization with the appropriate alkyl halide. b-Elimination yields the tertiary amine.
Literature
L 43
Please select a subcategory:
B7.4.1 Acrylic Ester attached to Polar PEG Spacer Resins
HypoGel® REM Resins
货号 名称 particle size capacity 包装
SP200110150 180 HypoGel® 200 REM 110 - 150 µm 0.6 - 0.8 mmol/g 5g
SP200110150 180 HypoGel® 200 REM 110 - 150 µm 0.6 - 0.8 mmol/g 25g
SP200110150 180 HypoGel® 200 REM 110 - 150 µm 0.6 - 0.8 mmol/g 100g
SP400110150 180 HypoGel® 400 REM 110 - 150 µm 0.5 - 0.6 mmol/g 5g
SP400110150 180 HypoGel® 400 REM 110 - 150 µm 0.5 - 0.6 mmol/g 25g
SP400110150 180 HypoGel® 400 REM 110 - 150 µm 0.5 - 0.6 mmol/g 100g
TentaGel® REM Resins
货号 名称 particle size capacity 包装
HL 12 018 TentaGel® HL REM 75 µm 0.3 - 0.5 mmol/g 5g
HL 12 018 TentaGel® HL REM 75 µm 0.3 - 0.5 mmol/g 25g
HL 12 018 TentaGel® HL REM 75 µm 0.3 - 0.5 mmol/g 100g
B7.4.2 Polystyrene REM Resins
货号 名称 particle size capacity 包装
HA 1 100 18 Polystyrene A REM 100 - 200 mesh 0.8 - 1.3 mmol/g 5g
HA 1 100 18 Polystyrene A REM 100 - 200 mesh 0.8 - 1.3 mmol/g 25g
HA 1 100 18 Polystyrene A REM 100 - 200 mesh 0.8 - 1.3 mmol/g 100g
HA 1 400 18 Polystyrene A REM 200 - 400 mesh 0.8 - 1.3 mmol/g 5g
HA 1 400 18 Polystyrene A REM 200 - 400 mesh 0.8 - 1.3 mmol/g 25g
HA 1 400 18 Polystyrene A REM 200 - 400 mesh 0.8 - 1.3 mmol/g 100g
HA 125160 18 Polystyrene A REM 125 - 160 µm 0.8 - 1.3 mmol/g 5g
HA 125160 18 Polystyrene A REM 125 - 160 µm 0.8 - 1.3 mmol/g 25g
HA 125160 18 Polystyrene A REM 125 - 160 µm 0.8 - 1.3 mmol/g 100g
HA 160200 18 Polystyrene A REM 160 - 200 µm 0.8 - 1.0 mmol/g 5g
HA 160200 18 Polystyrene A REM 160 - 200 µm 0.8 - 1.0 mmol/g 25g
HA 160200 18 Polystyrene A REM 160 - 200 µm 0.8 - 1.0 mmol/g 100g
HA 250315 18 Polystyrene A REM 250 - 315 µm 0.7 - 1.0 mmol/g 5g
HA 250315 18 Polystyrene A REM 250 - 315 µm 0.7 - 1.0 mmol/g 25g
HA 250315 18 Polystyrene A REM 250 - 315 µm 0.7 - 1.0 mmol/g 100g
HA 400450 18 Polystyrene A REM 400 - 450 µm 0.7 - 1.0 mmol/g 5g
HA 400450 18 Polystyrene A REM 400 - 450 µm 0.7 - 1.0 mmol/g 25g
HA 400450 18 Polystyrene A REM 400 - 450 µm 0.7 - 1.0 mmol/g 100g
HA 500560 18 Polystyrene A REM 500 - 560 µm 0.7 - 1.0 mmol/g 5g
HA 500560 18 Polystyrene A REM 500 - 560 µm 0.7 - 1.0 mmol/g 25g
HA 500560 18 Polystyrene A REM 500 - 560 µm 0.7 - 1.0 mmol/g 100g

B7.5 Resins with Acid Labile Linkers

B7.5.1 Resins for Amine and Amide Terminated Compounds
B7.5.1.1 Rink-Amide Linker on Aminoethyl Polystyrene Resins
货号 名称 particle size capacity 包装
HA 1 100 23 Polystyrene A RAM 100 - 200 mesh 0.6 - 0.8 mmol/g 5g
HA 1 100 23 Polystyrene A RAM 100 - 200 mesh 0.6 - 0.8 mmol/g 25g
HA 1 100 23 Polystyrene A RAM 100 - 200 mesh 0.6 - 0.8 mmol/g 100g
HA 1 400 23 Polystyrene A RAM 200 - 400 mesh 0.6 - 0.8 mmol/g 5g
HA 1 400 23 Polystyrene A RAM 200 - 400 mesh 0.6 - 0.8 mmol/g 25g
HA 1 400 23 Polystyrene A RAM 200 - 400 mesh 0.6 - 0.8 mmol/g 100g
HA 125160 23 Polystyrene A RAM 125 - 160 µm 0.4 - 0.7 mmol/g 5g
HA 125160 23 Polystyrene A RAM 125 - 160 µm 0.4 - 0.7 mmol/g 25g
HA 125160 23 Polystyrene A RAM 125 - 160 µm 0.4 - 0.7 mmol/g 100g
HA 160200 23 Polystyrene A RAM 160 - 200 µm 0.4 - 0.7 mmol/g 5g
HA 160200 23 Polystyrene A RAM 160 - 200 µm 0.4 - 0.7 mmol/g 25g
HA 160200 23 Polystyrene A RAM 160 - 200 µm 0.4 - 0.7 mmol/g 100g
HA 250315 23 Polystyrene A RAM 250 - 315 µm 0.4 - 0.7 mmol/g 5g
HA 250315 23 Polystyrene A RAM 250 - 315 µm 0.4 - 0.7 mmol/g 25g
HA 250315 23 Polystyrene A RAM 250 - 315 µm 0.4 - 0.7 mmol/g 100g
HA 400450 23 Polystyrene A RAM 400 - 450 µm 0.4 - 0.7 mmol/g 5g
HA 400450 23 Polystyrene A RAM 400 - 450 µm 0.4 - 0.7 mmol/g 25g
HA 400450 23 Polystyrene A RAM 400 - 450 µm 0.4 - 0.7 mmol/g 100g
HA 500560 23 Polystyrene A RAM 500 - 560 µm 0.4 - 0.7 mmol/g 5g
HA 500560 23 Polystyrene A RAM 500 - 560 µm 0.4 - 0.7 mmol/g 25g
HA 500560 23 Polystyrene A RAM 500 - 560 µm 0.4 - 0.7 mmol/g 100g
B7.5.1.2 Rink-Amide Linker on Aminomethyl Polystyrene Resins
货号 名称 particle size capacity 包装
H 100 23 Polystyrene AM RAM 100 - 200 mesh 0.6 - 0.8 mmol/g 5g
H 100 23 Polystyrene AM RAM 100 - 200 mesh 0.6 - 0.8 mmol/g 25g
H 100 23 Polystyrene AM RAM 100 - 200 mesh 0.6 - 0.8 mmol/g 100g
H 400 23 Polystyrene AM RAM 200 - 400 mesh 0.6 - 0.8 mmol/g 5g
H 400 23 Polystyrene AM RAM 200 - 400 mesh 0.6 - 0.8 mmol/g 25g
H 400 23 Polystyrene AM RAM 200 - 400 mesh 0.6 - 0.8 mmol/g 100g
H 125160 23 Polystyrene AM RAM 125 - 160 µm 0.4 - 0.7 mmol/g 5g
H 125160 23 Polystyrene AM RAM 125 - 160 µm 0.4 - 0.7 mmol/g 25g
H 125160 23 Polystyrene AM RAM 125 - 160 µm 0.4 - 0.7 mmol/g 100g
H 160200 23 Polystyrene AM RAM 160 - 200 µm 0.4 - 0.7 mmol/g 5g
H 160200 23 Polystyrene AM RAM 160 - 200 µm 0.4 - 0.7 mmol/g 25g
H 160200 23 Polystyrene AM RAM 160 - 200 µm 0.4 - 0.7 mmol/g 100g
H 250315 23 Polystyrene AM RAM 250 - 315 µm 0.4 - 0.7 mmol/g 5g
H 250315 23 Polystyrene AM RAM 250 - 315 µm 0.4 - 0.7 mmol/g 25g
H 250315 23 Polystyrene AM RAM 250 - 315 µm 0.4 - 0.7 mmol/g 100g
H 400450 23 Polystyrene AM RAM 400 - 450 µm 0.4 - 0.7 mmol/g 5g
H 400450 23 Polystyrene AM RAM 400 - 450 µm 0.4 - 0.7 mmol/g 25g
H 400450 23 Polystyrene AM RAM 400 - 450 µm 0.4 - 0.7 mmol/g 100g
H 500560 23 Polystyrene AM RAM 500 - 560 µm 0.4 - 0.7 mmol/g 5g
H 500560 23 Polystyrene AM RAM 500 - 560 µm 0.4 - 0.7 mmol/g 25g
H 500560 23 Polystyrene AM RAM 500 - 560 µm 0.4 - 0.7 mmol/g 100g
B7.5.1.3 Rink-Amide Linker on HypoGel® Resins
货号 名称 particle size capacity 包装
SP200 110150 230 HypoGel® 200 RAM 110 - 150 µm 0.6 - 0.7 mmol/g 5g
SP200 110150 230 HypoGel® 200 RAM 110 - 150 µm 0.6 - 0.7 mmol/g 25g
SP200 110150 230 HypoGel® 200 RAM 110 - 150 µm 0.6 - 0.7 mmol/g 100g
SP400 110150 230 HypoGel® 400 RAM 110 - 150 µm 0.5 - 0.6 mmol/g 5g
SP400 110150 230 HypoGel® 400 RAM 110 - 150 µm 0.5 - 0.6 mmol/g 25g
SP400 110150 230 HypoGel® 400 RAM 110 - 150 µm 0.5 - 0.6 mmol/g 100g
B7.5.1.4 Rink-Amide Linker on TentaGel® Resins
B7.5.1.4.1 TentaGel® HL RAM RAM Linker Attached to High Loaded TentaGel Resins
This highloaded version of TentaGel® combines a significantly higher capacity with the advantages of TentaGel® resins. The spacer is in the range of MW 1500 - 2000 Da.
This resin is functionalized with a modified Rink Amide linker and is ideal for the Fmoc SPPS of peptide amides. Cleavage from this support is achieved with 95 % TFA.
货号 名称 particle size capacity 包装
HL 12 023 TentaGel® HL RAM 75 µm 0.3 - 0.4 mmol/g 1g
HL 12 023 TentaGel® HL RAM 75 µm 0.3 - 0.4 mmol/g 5g
HL 12 023 TentaGel® HL RAM 75 µm 0.3 - 0.4 mmol/g 25g
HL 12 023 TentaGel® HL RAM 75 µm 0.3 - 0.4 mmol/g 100g
B7.5.1.4.2 TentaGel® MB RAM RAM Linker Attached to TentaGel Macrobeads
TentaGel® Macrobeads are highlighted by extraordinary large particle diameters and high capacities based on the TentaGel® technology and designed for single bead synthesis and single bead analysis.
This resin is functionalized with a modified Rink Amide linker and is ideal for the Fmoc SPPS of peptide amides. Cleavage from this support is achieved with 95 % TFA.
Literature
L 3
货号 名称 particle size capacity 包装
MB 160 230 TentaGel® MB RAM 140 - 170 µm 0.3 - 0.4 mmol/g 1g
MB 160 230 TentaGel® MB RAM 140 - 170 µm 0.3 - 0.4 mmol/g 5g
MB 160 230 TentaGel® MB RAM 140 - 170 µm 0.3 - 0.4 mmol/g 25g
MB 160 230 TentaGel® MB RAM 140 - 170 µm 0.3 - 0.4 mmol/g 100g
MB 250 230 TentaGel® MB RAM 200 - 250 µm 0.2 - 0.3 mmol/g 1g
MB 250 230 TentaGel® MB RAM 200 - 250 µm 0.2 - 0.3 mmol/g 5g
MB 250 230 TentaGel® MB RAM 200 - 250 µm 0.2 - 0.3 mmol/g 25g
MB 250 230 TentaGel® MB RAM 200 - 250 µm 0.2 - 0.3 mmol/g 100g
MB 250 230 TentaGel® MB RAM 280 - 320 µm 0.2 - 0.3 mmol/g 1g
MB 250 230 TentaGel® MB RAM 280 - 320 µm 0.2 - 0.3 mmol/g 5g
MB 300 230 TentaGel® MB RAM 280 - 320 µm 0.2 - 0.3 mmol/g 25g
MB 300 230 TentaGel® MB RAM 280 - 320 µm 0.2 - 0.3 mmol/g 100g
B7.5.1.4.3 TentaGel® R RAM RAM Linker Attached to TentaGel Research Resins
TentaGel® resins are grafted copolymers consisting of a low crosslinked polystyrene matrix on which polyethylene glycol (PEG or POE) is grafted. The PEG spacer is attached to the matrix via an ethyl ether group which increases stability towards acid treatment and minimizes PEG-leaching. As PEG is a "chameleon type" polymer with hydrophobic and hydrophilic properties, the graft copolymer shows modified physico chemical properties which are highly dominated by the PEG moiety (and no longer by the polystyrene matrix). These graft copolymers are pressure stable and can be used in batch processes as well as under continuous flow conditions. The PEG spacer is in the range of MW 3000 Da.
TentaGel® R represents a special designed resin for research synthesis. Long peptide sequences (up to 100 residues) and difficult sequences are synthesized on this support. The resin shows an increased swelling volume and a significant lower loading.
This resin is functionalized with a modified Rink Amide linker and is ideal for the Fmoc SPPS of peptide amides. Cleavage from this support is achieved by 95 % TFA.
Literature
L 4, L 5, L 6, L 7, L 24, L 25; ee also: General Information
货号 名称 particle size capacity 包装
R 28 023 TentaGel® R RAM 90 µm 0.18 - 0.22 mmol/g 1g
R 28 023 TentaGel® R RAM 90 µm 0.18 - 0.22 mmol/g 5g
R 28 023 TentaGel® R RAM 90 µm 0.18 - 0.22 mmol/g 25g
R 28 023 TentaGel® R RAM 90 µm 0.18 - 0.22 mmol/g 50g
B7.5.1.4.4 TentaGel® S RAM RAM Linker Attached to Standard TentaGel Resins
Standard resin for a large number of applications, useful in batch and flow through systems. This resin is recommended for synthesis of standard peptide amides up to 40 residues in length.
This resin is functionalized with a modified Rink Amide linker and is ideal for the Fmoc SPPS of peptide amides. Cleavage from this support is achieved by 95 % TFA.
货号 名称 particle size capacity 包装
S 30 023 TentaGel® S RAM 90 µm 0.2 - 0.27 mmol/g 1g
S 30 023 TentaGel® S RAM 90 µm 0.2 - 0.27 mmol/g 5g
S 30 023 TentaGel® S RAM 90 µm 0.2 - 0.27 mmol/g 25g
S 30 023 TentaGel® S RAM 90 µm 0.2 - 0.27 mmol/g 100g
B7.5.2 Resins for Carboxy Terminated Compounds
B7.5.2.1 3-Methoxy-4-(Hydroxymethyl) Phenoxyacetic Acid Based Resins (AC-Linker) on TentaGel®
B7.5.2.1.1 TentaGel® HL AC AC Linker on High Loaded TentaGel Resins
货号 名称 particle size capacity 包装
HL 12 011 TentaGel® HL AC 75 µm 0.3 - 0.4 mmol/g 1g
HL 12 011 TentaGel® HL AC 75 µm 0.3 - 0.4 mmol/g 5g
HL 12 011 TentaGel® HL AC 75 µm 0.3 - 0.4 mmol/g 25g
HL 12 011 TentaGel® HL AC 75 µm 0.3 - 0.4 mmol/g 50g
B7.5.2.1.2 TentaGel® MB AC AC Linker on TentaGel Macrobead Resins
货号 名称 particle size capacity 包装
MB 160 110 TentaGel® MB AC 140 - 170 µm 0.4 - 0.6 mmol/g 1g
MB 160 110 TentaGel® MB AC 140 - 170 µm 0.4 - 0.6 mmol/g 5g
MB 160 110 TentaGel® MB AC 140 - 170 µm 0.4 - 0.6 mmol/g 25g
MB 160 110 TentaGel® MB AC 140 - 170 µm 0.4 - 0.6 mmol/g 50g
MB 250 110 TentaGel® MB AC 200 - 250 µm 0.2 - 0.3 mmol/g 1g
MB 250 110 TentaGel® MB AC 200 - 250 µm 0.2 - 0.3 mmol/g 5g
MB 250 110 TentaGel® MB AC 200 - 250 µm 0.2 - 0.3 mmol/g 25g
MB 250 110 TentaGel® MB AC 200 - 250 µm 0.2 - 0.3 mmol/g 50g
MB 300 110 TentaGel® MB AC 280 - 320 µm 0.2 - 0.3 mmol/g 1g
MB 300 110 TentaGel® MB AC 280 - 320 µm 0.2 - 0.3 mmol/g 5g
MB 300 110 TentaGel® MB AC 280 - 320 µm 0.2 - 0.3 mmol/g 25g
MB 300 110 TentaGel® MB AC 280 - 320 µm 0.2 - 0.3 mmol/g 50g
B7.5.2.1.3 TentaGel® S AC AC Linker on Standard TentaGel Resins
Standard resin for a large number of applications, useful in batch and flow through systems.
Esters can be cleaved by 1-5% TFA in CH?Cl?.
货号 名称 particle size capacity 包装
S 30 011 TentaGel® S AC 90 µm 0.2 - 0.3 mmol/g 1g
S 30 011 TentaGel® S AC 90 µm 0.2 - 0.3 mmol/g 5g
S 30 011 TentaGel® S AC 90 µm 0.2 - 0.3 mmol/g 25g
S 30 011 TentaGel® S AC 90 µm 0.2 - 0.3 mmol/g 50g
B7.5.2.2 HMPA Polystyrene Resins
B7.5.2.2.1 4-(Hydroxymethyl) Phenoxyacetic Acid (HMPA) on Aminoethyl Polystyrene Resins
货号 名称 particle size capacity 包装
HA 1 100 15 Polystyrene A HMPA 100 - 200 mesh 0.8 - 1.2 mmol/g 5g
HA 1 100 15 Polystyrene A HMPA 100 - 200 mesh 0.8 - 1.2 mmol/g 25g
HA 1 100 15 Polystyrene A HMPA 100 - 200 mesh 0.8 - 1.2 mmol/g 100g
HA 1 400 15 Polystyrene A HMPA 200 - 400 mesh 0.8 - 1.2 mmol/g 5g
HA 1 400 15 Polystyrene A HMPA 200 - 400 mesh 0.8 - 1.2 mmol/g 25g
HA 1 400 15 Polystyrene A HMPA 200 - 400 mesh 0.8 - 1.2 mmol/g 100g
HA 125160 15 Polystyrene A HMPA 125 - 160 µm 0.8 - 1.2 mmol/g 5g
HA 125160 15 Polystyrene A HMPA 125 - 160 µm 0.8 - 1.2 mmol/g 25g
HA 125160 15 Polystyrene A HMPA 125 - 160 µm 0.8 - 1.2 mmol/g 100g
HA 160200 15 Polystyrene A HMPA 160 - 200 µm 0.8 - 1.2 mmol/g 5g
HA 160200 15 Polystyrene A HMPA 160 - 200 µm 0.8 - 1.2 mmol/g 25g
HA 160200 15 Polystyrene A HMPA 160 - 200 µm 0.8 - 1.2 mmol/g 100g
HA 250315 15 Polystyrene A HMPA 250 - 315 µm 0.6 - 1.0 mmol/g 5g
HA 250315 15 Polystyrene A HMPA 250 - 315 µm 0.6 - 1.0 mmol/g 25g
HA 250315 15 Polystyrene A HMPA 250 - 315 µm 0.6 - 1.0 mmol/g 100g
HA 400450 15 Polystyrene A HMPA 400 - 450 µm 0.6 - 1.0 mmol/g 5g
HA 400450 15 Polystyrene A HMPA 400 - 450 µm 0.6 - 1.0 mmol/g 25g
HA 400450 15 Polystyrene A HMPA 400 - 450 µm 0.6 - 1.0 mmol/g 100g
HA 500560 15 Polystyrene A HMPA 500 - 560 µm 0.6 - 1.0 mmol/g 5g
HA 500560 15 Polystyrene A HMPA 500 - 560 µm 0.6 - 1.0 mmol/g 25g
HA 500560 15 Polystyrene A HMPA 500 - 560 µm 0.6 - 1.0 mmol/g 100g
B7.5.2.2.2 4-(Hydroxymethyl) Phenoxyacetic Acid (HMPA) on Aminomethyl Polystyrene Resins
This resin is derivatized from aminomethyl polystyrene by coupling with the TFA-labile 4-(hydroxymethyl)-phenoxyacetic acid linker and is an alternative to the PHB resins.
货号 名称 particle size capacity 包装
H 100 15 Polystyrene AM HMPA 100 - 200 mesh 0.8 - 1.2 mmol/g 5g
H 100 15 Polystyrene AM HMPA 100 - 200 mesh 0.8 - 1.2 mmol/g 25g
H 100 15 Polystyrene AM HMPA 100 - 200 mesh 0.8 - 1.2 mmol/g 100g
H 400 15 Polystyrene AM HMPA 200 - 400 mesh 0.8 - 1.2 mmol/g 5g
H 400 15 Polystyrene AM HMPA 200 - 400 mesh 0.8 - 1.2 mmol/g 25g
H 400 15 Polystyrene AM HMPA 200 - 400 mesh 0.8 - 1.2 mmol/g 100g
H 125160 15 Polystyrene AM HMPA 125 - 160 µm 0.8 - 1.2 mmol/g 5g
H 125160 15 Polystyrene AM HMPA 125 - 160 µm 0.8 - 1.2 mmol/g 25g
H 125160 15 Polystyrene AM HMPA 125 - 160 µm 0.8 - 1.2 mmol/g 100g
H 160200 15 Polystyrene AM HMPA 160 - 200 µm 0.8 - 1.2 mmol/g 5g
H 160200 15 Polystyrene AM HMPA 160 - 200 µm 0.8 - 1.2 mmol/g 25g
H 160200 15 Polystyrene AM HMPA 160 - 200 µm 0.8 - 1.2 mmol/g 100g
H 250315 15 Polystyrene AM HMPA 250 - 315 µm 0.6 - 1.0 mmol/g 5g
H 250315 15 Polystyrene AM HMPA 250 - 315 µm 0.6 - 1.0 mmol/g 25g
H 250315 15 Polystyrene AM HMPA 250 - 315 µm 0.6 - 1.0 mmol/g 100g
H 400450 15 Polystyrene AM HMPA 400 - 450 µm 0.6 - 1.0 mmol/g 5g
H 400450 15 Polystyrene AM HMPA 400 - 450 µm 0.6 - 1.0 mmol/g 25g
H 400450 15 Polystyrene AM HMPA 400 - 450 µm 0.6 - 1.0 mmol/g 100g
H 500560 15 Polystyrene AM HMPA 500 - 560 µm 0.6 - 1.0 mmol/g 5g
H 500560 15 Polystyrene AM HMPA 500 - 560 µm 0.6 - 1.0 mmol/g 25g
H 500560 15 Polystyrene AM HMPA 500 - 560 µm 0.6 - 1.0 mmol/g 100g
B7.5.2.3 Para Hydroxybenzyl Alcohol ( PHB, Wang Linker) attached to TentaGel® Resins
B7.5.2.3.1 TentaGel® HL PHB PHB Attached to High Loaded TentaGel Resins
货号 名称 particle size capacity 包装
HL12 013 TentaGel® HL PHB 75 µm 0.3 - 0.4 mmol/g 1g
HL12 013 TentaGel® HL PHB 75 µm 0.3 - 0.4 mmol/g 5g
HL12 013 TentaGel® HL PHB 75 µm 0.3 - 0.4 mmol/g 25g
B7.5.2.3.2 TentaGel® MB PHB PHB Attached to TentaGel Macrobead Resins
TentaGel® Macrobeads are highlighted by extraordinary large particle diameters and high capacities based on the TentaGel® technology and designed for single bead synthesis and single bead analysis.
货号 名称 particle size capacity 包装
MB 160 130 TentaGel® MB PHB 140 - 170 µm 0.3 - 0.5 mmol/g 1g
MB 160 130 TentaGel® MB PHB 140 - 170 µm 0.3 - 0.5 mmol/g 5g
MB 160 130 TentaGel® MB PHB 140 - 170 µm 0.3 - 0.5 mmol/g 25g
MB 250 130 TentaGel® MB PHB 200 - 250 µm 0.2 - 0.3 mmol/g 1g
MB 250 130 TentaGel® MB PHB 200 - 250 µm 0.2 - 0.3 mmol/g 5g
MB 250 130 TentaGel® MB PHB 200 - 250 µm 0.2 - 0.3 mmol/g 25g
MB 300 130 TentaGel® MB PHB 280 - 320 µm 0.2 - 0.3 mmol/g 1g
MB 300 130 TentaGel® MB PHB 280 - 320 µm 0.2 - 0.3 mmol/g 5g
MB 300 130 TentaGel® MB PHB 280 - 320 µm 0.2 - 0.3 mmol/g 25g
B7.5.2.3.3 TentaGel® R PHB PHB Attached to TentaGel Research Resins
A special designed resin for research synthesis. Long peptide sequences (up to 100 residues), difficult sequences and PNA´s are synthesized on this support. The resin shows an increased swelling volume and a significant lower loading.
货号 名称 particle size capacity 包装
R 28 013 TentaGel® R PHB 90 µm 0.18 - 0.23 mmol/g 1g
R 28 013 TentaGel® R PHB 90 µm 0.18 - 0.23 mmol/g 5g
R 28 013 TentaGel® R PHB 90 µm 0.18 - 0.23 mmol/g 25g
R 28 013 TentaGel® R PHB 90 µm 0.18 - 0.23 mmol/g 50g
B7.5.2.3.4 TentaGel® S PHB PHB Attached to Standard TentaGel Resins
Standard resin for a large number of applications, useful in batch and flow through systems. This resin is recommended for synthesis of standard peptides up to 40 residues in length.
货号 名称 particle size capacity 包装
S 30 013 TentaGel® S PHB 90 µm 0.2 - 0.3 mmol/g 1g
S 30 013 TentaGel® S PHB 90 µm 0.2 - 0.3 mmol/g 5g
S 30 013 TentaGel® S PHB 90 µm 0.2 - 0.3 mmol/g 25g
S 30 013 TentaGel® S PHB 90 µm 0.2 - 0.3 mmol/g 100g
B7.5.2.4 Para Hydroxybenzyl Alcohol ( PHB, Wang Linker) on HypoGel® Resins
HypoGel® is a hydrophilic gel type resin which combines high capacities with good solvent compatibility. Glycol spacers with n = 5 or 10 EO units separate the reactive sites from the polystyrene matrix and modify the hydrophobic properties of the polystyrene backbone. Due to the spacer effect the functional group shows a higher mobility which results in higher kinetic rates and high resolution NMR spectra from immobilized compounds on the bead. The resin is compatible to a wide range of solvents and in contrast to polystyrene even polar solvents like methanol or ethanol can be used.
These resins show high capacities and a hydrophilicity between polystyrene and TentaGel®
The parahydroxybencyl alcohol attached to TentaGel make this resin ideal for attaching carboxylic acids for further functionalisation and peptide synthesis. Cleavage conditions are concentrated TFA or TFA/CH?CI? mixtures to provide carboxylic acids, peptides or cyclization-cleavage under acidic or basic conditions. This resin is recommended for the synthesis of short peptides (10 - 15 residues).
Literature
L 17
货号 名称 particle size capacity 包装
SP200 110150 130 HypoGel® 200 PHB 110 - 150 µm 0.6 - 0.8 mmol/g 5g
SP200 110150 130 HypoGel® 200 PHB 110 - 150 µm 0.6 - 0.8 mmol/g 25g
SP200 110150 130 HypoGel® 200 PHB 110 - 150 µm 0.6 - 0.8 mmol/g 100g
SP400 110150 130 HypoGel® 400 PHB 110 - 150 µm 0.4 - 0.6 mmol/g 5g
SP400 110150 130 HypoGel® 400 PHB 110 - 150 µm 0.4 - 0.6 mmol/g 25g
SP400 110150 130 HypoGel® 400 PHB 110 - 150 µm 0.4 - 0.6 mmol/g 100g
B7.5.2.5 Parahydroxybenzyl Alcohol Polystyrene Resins (PHB, Wang-type)
B7.5.2.5.1 Para Hydroxybenzyl Alcohol (PHB, Wang Linker ) on Ethylated Polystyrene Matrix
货号 名称 particle size capacity 包装
HA 1 100 13 Polystyrene A PHB 100 - 200 mesh 0.5 - 1.0 mmol/g 5g
HA 1 100 13 Polystyrene A PHB 100 - 200 mesh 0.5 - 1.0 mmol/g 25g
HA 1 100 13 Polystyrene A PHB 100 - 200 mesh 0.5 - 1.0 mmol/g 100g
HA 1 400 13 Polystyrene A PHB 200 - 400 mesh 0.5 - 1.0 mmol/g 5g
HA 1 400 13 Polystyrene A PHB 200 - 400 mesh 0.5 - 1.0 mmol/g 25g
HA 1 400 13 Polystyrene A PHB 200 - 400 mesh 0.5 - 1.0 mmol/g 100g
HA 125160 13 Polystyrene A PHB 125 - 160 µm 0.5 - 1.0 mmol/g 5g
HA 125160 13 Polystyrene A PHB 125 - 160 µm 0.5 - 1.0 mmol/g 25g
HA 125160 13 Polystyrene A PHB 125 - 160 µm 0.5 - 1.0 mmol/g 100g
HA 160200 13 Polystyrene A PHB 160 - 200 µm 0.5 - 0.8 mmol/g 5g
HA 160200 13 Polystyrene A PHB 160 - 200 µm 0.5 - 0.8 mmol/g 25g
HA 160200 13 Polystyrene A PHB 160 - 200 µm 0.5 - 0.8 mmol/g 100g
HA 250315 13 Polystyrene A PHB 250 - 315 µm 0.5 - 0.8 mmol/g 5g
HA 250315 13 Polystyrene A PHB 250 - 315 µm 0.5 - 0.8 mmol/g 25g
HA 250315 13 Polystyrene A PHB 250 - 315 µm 0.5 - 0.8 mmol/g 100g
HA 400450 13 Polystyrene A PHB 400 - 450 µm 0.5 - 0.8 mmol/g 5g
HA 400450 13 Polystyrene A PHB 400 - 450 µm 0.5 - 0.8 mmol/g 25g
HA 400450 13 Polystyrene A PHB 400 - 450 µm 0.5 - 0.8 mmol/g 100g
HA 500560 13 Polystyrene A PHB 500 - 560 µm 0.5 - 0.8 mmol/g 5g
HA 500560 13 Polystyrene A PHB 500 - 560 µm 0.5 - 0.8 mmol/g 25g
HA 500560 13 Polystyrene A PHB 500 - 560 µm 0.5 - 0.8 mmol/g 100g
B7.5.2.5.2 Para Hydroxybenzyl Alcohol (PHB, Wang Linker) on Butylated Polystyrene Matrix
The linker is separated by a C4 spacer from the crosslinked matrix. Due to this spacer effect the functional group shows a higher mobility which results in higher kinetic rates and high resolution NMR spectra from immobilized compounds on the bead.
货号 名称 particle size capacity 包装
HB 045080 13 Polystyrene C4 PHB 45 - 80 µm 0.8 - 1.2 mmol/g 5g
HB 045080 13 Polystyrene C4 PHB 45 - 80 µm 0.8 - 1.2 mmol/g 25g
HB 045080 13 Polystyrene C4 PHB 45 - 80 µm 0.8 - 1.2 mmol/g 100g
HB 080160 13 Polystyrene C4 PHB 80 - 160 µm 0.8 - 1.2 mmol/g 5g
HB 080160 13 Polystyrene C4 PHB 80 - 160 µm 0.8 - 1.2 mmol/g 25g
HB 080160 13 Polystyrene C4 PHB 80 - 160 µm 0.8 - 1.2 mmol/g 100g
HB 125160 13 Polystyrene C4 PHB 125 - 160 µm 0.8 - 1.2 mmol/g 5g
HB 125160 13 Polystyrene C4 PHB 125 - 160 µm 0.8 - 1.2 mmol/g 25g
HB 125160 13 Polystyrene C4 PHB 125 - 160 µm 0.8 - 1.2 mmol/g 100g
B7.5.2.5.3 Wang Resin - Para Hydroxybenzyl Alcohol (PHB) on Polystyrene
The Wang support is the most widely used resin for attaching carboxylic acids for further functionalisation. Cleavage conditions for the ester anchor involve concentrated TFA or TFA/CH?CI? mixtures to provide carboxylic acids or cyclization-cleavage under acidic or basic conditions. Release of an amide function by treatment with an amine in the presence of a Lewis acid was also reported. Wang resin was used to add vinyl and iodobenzoic acids via carbodiimide coupling and the products subjected to Heck conditions with alkenes or with alkynes or to Suzuki coupling with boron reagents. The Ugi multicomponent condensation reaction was conducted on Wang resin with the carboxylic acid, amine or isonitrile as the anchored functional group. On a Wang resin primary, secondary, and tertiary alcohols have been converted to 4-methoxy-benzyl ethers. As well as anchoring carboxylic acids to this resin, phenols were attached under Mitsunobu conditions, subjected to further transformations and cleaved under acidic conditions.
Solid-phase lactam syntheses were also achieved by reaction of the resin-bound isonitrile with an amine and an w-keto-acid as well as other synthetic transformations such as the Biginelli reaction and construction of heterocycles such as quinolones, imidazoles, hydantoins, and 1,4-benzodiazepine-2,5-diones.
Literature
L 39
货号 名称 particle size capacity 包装
H 100 13 Polystyrene PHB (Wang resin) 100 - 200 mesh 0.8 - 1.25 mmol/g 5g
H 100 13 Polystyrene PHB (Wang resin) 100 - 200 mesh 0.8 - 1.25 mmol/g 25g
H 100 13 Polystyrene PHB (Wang resin) 100 - 200 mesh 0.8 - 1.25 mmol/g 100g
H 400 13 Polystyrene PHB (Wang resin) 200 - 400 mesh 0.8 - 1.25 mmol/g 5g
H 400 13 Polystyrene PHB (Wang resin) 200 - 400 mesh 0.8 - 1.25 mmol/g 25g
H 400 13 Polystyrene PHB (Wang resin) 200 - 400 mesh 0.8 - 1.25 mmol/g 100g
H 125160 13 Polystyrene PHB (Wang resin) 125 - 160 µm 0.8 - 1.25 mmol/g 5g
H 125160 13 Polystyrene PHB (Wang resin) 125 - 160 µm 0.8 - 1.25 mmol/g 25g
H 125160 13 Polystyrene PHB (Wang resin) 125 - 160 µm 0.8 - 1.25 mmol/g 100g
B7.5.3 Resins for Protected Peptide Amides
TOPPA - A Novel Resin for Synthesis of Protected Peptide Amides
This resin type is based on a TentaGel or polystyrene matrix and combines the very acid sensitive trityl handle with the acid sensitive Rink amide handle. The peptide synthesis can be performed by standard conditions. Treatment of the TOPPA resin with diluted AcOH, TFE or mixtures of both in dichloromethane cleaves the trityl ester bond and releases the total protected peptide amide (TOPPA). The C-terminus of the protected peptide amide is still masked by the Rink handle.
Literature
L 50
Please select a subcategory:
B7.5.3.1 Protected Amides from Polystyrene Resins
货号 名称 particle size capacity 包装
H 75150.033023 PS TOPPA 75 - 150 µm 0.6 - 0.9 mmol/g 1g
H 75150.033023 PS TOPPA 75 - 150 µm 0.6 - 0.9 mmol/g 5g
H 75150.033023 PS TOPPA 75 - 150 µm 0.6 - 0.9 mmol/g 25g
B7.5.3.2 Protected Amides from TentaGel Resins
货号 名称 particle size capacity 包装
S 30902.012023 TentaGel® TOPPA 90 µm 0.18 - 0.25 mmol/g 1g
S 30902.012023 TentaGel® TOPPA 90 µm 0.18 - 0.25 mmol/g 5g
S 30902.012023 TentaGel® TOPPA 90 µm 0.18 - 0.25 mmol/g 25g
B7.5.4 Resins for the Synthesis of Thioesters
Trityl Mercapto Acetyl Leu PAM loaded to Aminomethyl Polystyrene
This resin can be used for the synthesis of peptide thioesters by Boc chemistry. After removal of the trityl protecting group by TFA/DCM treatment the first Boc amino acid is loaded to the resin by DIC/HOBt activation. Peptide synthesis follows the standard Boc synthesis protocol.
After finishing the peptide synthesis, the peptide thioester resin is treated by HF resulting in the deprotected peptide thioester derivative which can be used for native chemical ligation.
Literature
L 55
货号 名称 particle size capacity 包装
H 100 90 Polystyrene AM PAM Leu Acetyl Mercapto Trt 100 - 200 mesh 0.6 - 0.9 mmol/g 1g
H 100 90 Polystyrene AM PAM Leu Acetyl Mercapto Trt 100 - 200 mesh 0.6 - 0.9 mmol/g 5g
B7.5.5 Trityl Based Linkers
B7.5.5.1 Chloro-(2'-chloro)trityl Polystyrene Resins
A very acid sensitive resin suitable for the synthesis of protected peptide fragments by the Fmoc-strategy. In particular suitable for the preparation of C-terminal prolyl and cysteinyl peptides. Cleavage from this resin is achieved by using 1-95% TFA in CH?CI? (containing 8% triisopropylsilane), AcOH/CF?OH/CH?CI?, 0.5% TFA or hexafluoroisopropanol. Recently, this resin has been used in cyclization reactions under Heck reaction conditions, the solid phase synthesis of b-peptides via the Arndt-Eistert homologation of Fmoc-protected amino acid diazoketones and in Mannich reactions of alkynes, secondary amines and aldehydes in the presence of a copper (I) salt affording the corresponding aminomethylalkynyl adducts.
This resin can also be used in Fmoc peptide synthesis. Carboxylic acids can be released under very mild acidic conditions by treatment with AcOH/TFE/DCM or HFIP in DCM. Completely protected peptides are generated under this condition.
Literature
L 37
货号 名称 particle size capacity 包装
H 100 33 Chloro-(2'-chloro)trityl Polystyrene 100 - 200 mesh 0.8 - 1.5 mmol/g 5g
H 100 33 Chloro-(2'-chloro)trityl Polystyrene 100 - 200 mesh 0.8 - 1.5 mmol/g 25g
H 100 33 Chloro-(2'-chloro)trityl Polystyrene 100 - 200 mesh 0.8 - 1.5 mmol/g 100g
H 400 33 Chloro-(2'-chloro)trityl Polystyrene 200 - 400 mesh 0.8 - 1.5 mmol/g 5g
H 400 33 Chloro-(2'-chloro)trityl Polystyrene 200 - 400 mesh 0.8 - 1.5 mmol/g 25g
H 400 33 Chloro-(2'-chloro)trityl Polystyrene 200 - 400 mesh 0.8 - 1.5 mmol/g 100g
H 125160 33 Chloro-(2'-chloro)trityl Polystyrene 125 - 160 µm 0.8 - 1.5 mmol/g 5g
H 125160 33 Chloro-(2'-chloro)trityl Polystyrene 125 - 160 µm 0.8 - 1.5 mmol/g 25g
H 125160 33 Chloro-(2'-chloro)trityl Polystyrene 125 - 160 µm 0.8 - 1.5 mmol/g 100g
H 160200 33 Chloro-(2'-chloro)trityl Polystyrene 160 - 200 µm 0.8 - 1.3 mmol/g 5g
H 160200 33 Chloro-(2'-chloro)trityl Polystyrene 160 - 200 µm 0.8 - 1.3 mmol/g 25g
H 160200 33 Chloro-(2'-chloro)trityl Polystyrene 160 - 200 µm 0.8 - 1.3 mmol/g 100g
H 250315 33 Chloro-(2'-chloro)trityl Polystyrene 250 - 315 µm 0.6 - 1.0 mmol/g 5g
H 250315 33 Chloro-(2'-chloro)trityl Polystyrene 250 - 315 µm 0.6 - 1.0 mmol/g 25g
H 250315 33 Chloro-(2'-chloro)trityl Polystyrene 250 - 315 µm 0.6 - 1.0 mmol/g 100g
H 400450 33 Chloro-(2'-chloro)trityl Polystyrene 400 - 450 µm 0.6 - 1.0 mmol/g 5g
H 400450 33 Chloro-(2'-chloro)trityl Polystyrene 400 - 450 µm 0.6 - 1.0 mmol/g 25g
H 400450 33 Chloro-(2'-chloro)trityl Polystyrene 400 - 450 µm 0.6 - 1.0 mmol/g 100g
H 500560 33 Chloro-(2'-chloro)trityl Polystyrene 500 - 560 µm 0.6 - 1.0 mmol/g 5g
H 500560 33 Chloro-(2'-chloro)trityl Polystyrene 500 - 560 µm 0.6 - 1.0 mmol/g 25g
H 500560 33 Chloro-(2'-chloro)trityl Polystyrene 500 - 560 µm 0.6 - 1.0 mmol/g 100g
B7.5.5.2 Chlorotrityl Polystyrene Resins (Trityl Chloride Resin)
This highly acid labile resin is useful for the immobilization of alcohols, amines and carboxylic acids. Cleavage is in general achieved by using either 1-5 % TFA in CH?Cl? (containing 5 % triisopropylsilane) or acetic acid.
This resin can also be used in Fmoc peptide synthesis under basic acylation conditions. Carboxylic acids can be released under very mild acidic conditions by treatment with AcOH/TFE/DCM or HFIP in DCM. Completely protected peptides are generated under this conditions.
Literature
L 36
货号 名称 particle size capacity 包装
H 100 31 Chlorotrityl Polystyrene 100 - 200 mesh 0.8 - 1.5 mmol/g 5g
H 100 31 Chlorotrityl Polystyrene 100 - 200 mesh 0.8 - 1.5 mmol/g 25g
H 100 31 Chlorotrityl Polystyrene 100 - 200 mesh 0.8 - 1.5 mmol/g 100g
H 400 31 Chlorotrityl Polystyrene 200 - 400 mesh 0.8 - 1.5 mmol/g 5g
H 400 31 Chlorotrityl Polystyrene 200 - 400 mesh 0.8 - 1.5 mmol/g 25g
H 400 31 Chlorotrityl Polystyrene 200 - 400 mesh 0.8 - 1.5 mmol/g 100g
H 125160 31 Chlorotrityl Polystyrene 125 - 160 µm 0.8 - 1.5 mmol/g 5g
H 125160 31 Chlorotrityl Polystyrene 125 - 160 µm 0.8 - 1.5 mmol/g 25g
H 125160 31 Chlorotrityl Polystyrene 125 - 160 µm 0.8 - 1.5 mmol/g 100g
H 160200 31 Chlorotrityl Polystyrene 160 - 200 µm 0.8 - 1.3 mmol/g 5g
H 160200 31 Chlorotrityl Polystyrene 160 - 200 µm 0.8 - 1.3 mmol/g 25g
H 160200 31 Chlorotrityl Polystyrene 160 - 200 µm 0.8 - 1.3 mmol/g 100g
H 250315 31 Chlorotrityl Polystyrene 250 - 315 µm 0.6 - 1.0 mmol/g 5g
H 250315 31 Chlorotrityl Polystyrene 250 - 315 µm 0.6 - 1.0 mmol/g 25g
H 250315 31 Chlorotrityl Polystyrene 250 - 315 µm 0.6 - 1.0 mmol/g 100g
H 400450 31 Chlorotrityl Polystyrene 400 - 450 µm 0.6 - 1.0 mmol/g 5g
H 400450 31 Chlorotrityl Polystyrene 400 - 450 µm 0.6 - 1.0 mmol/g 25g
H 400450 31 Chlorotrityl Polystyrene 400 - 450 µm 0.6 - 1.0 mmol/g 100g
H 500560 31 Chlorotrityl Polystyrene 500 - 560 µm 0.6 - 1.0 mmol/g 5g
H 500560 31 Chlorotrityl Polystyrene 500 - 560 µm 0.6 - 1.0 mmol/g 25g
H 500560 31 Chlorotrityl Polystyrene 500 - 560 µm 0.6 - 1.0 mmol/g 100g
B7.5.5.3 Hydroxytrityl Polystyrene Resins
货号 名称 particle size capacity 包装
H 100 30 Hydroxytrityl Polystyrene 100 - 200 mesh 0.8 - 1.5 mmol/g 5g
H 100 30 Hydroxytrityl Polystyrene 100 - 200 mesh 0.8 - 1.5 mmol/g 25g
H 100 30 Hydroxytrityl Polystyrene 100 - 200 mesh 0.8 - 1.5 mmol/g 100g
H 400 30 Hydroxytrityl Polystyrene 200 - 400 mesh 0.8 - 1.5 mmol/g 5g
H 400 30 Hydroxytrityl Polystyrene 200 - 400 mesh 0.8 - 1.5 mmol/g 25g
H 400 30 Hydroxytrityl Polystyrene 200 - 400 mesh 0.8 - 1.5 mmol/g 100g
H 125160 30 Hydroxytrityl Polystyrene 125 - 160 µm 0.8 - 1.5 mmol/g 5g
H 125160 30 Hydroxytrityl Polystyrene 125 - 160 µm 0.8 - 1.5 mmol/g 25g
H 125160 30 Hydroxytrityl Polystyrene 125 - 160 µm 0.8 - 1.5 mmol/g 100g
H 160200 30 Hydroxytrityl Polystyrene 160 - 200 µm 0.8 - 1.3 mmol/g 5g
H 160200 30 Hydroxytrityl Polystyrene 160 - 200 µm 0.8 - 1.3 mmol/g 25g
H 160200 30 Hydroxytrityl Polystyrene 160 - 200 µm 0.8 - 1.3 mmol/g 100g
H 250315 30 Hydroxytrityl Polystyrene 250 - 315 µm 0.6 - 1.0 mmol/g 5g
H 250315 30 Hydroxytrityl Polystyrene 250 - 315 µm 0.6 - 1.0 mmol/g 25g
H 250315 30 Hydroxytrityl Polystyrene 250 - 315 µm 0.6 - 1.0 mmol/g 100g
H 400450 30 Hydroxytrityl Polystyrene 400 - 450 µm 0.6 - 1.0 mmol/g 5g
H 400450 30 Hydroxytrityl Polystyrene 400 - 450 µm 0.6 - 1.0 mmol/g 25g
H 400450 30 Hydroxytrityl Polystyrene 400 - 450 µm 0.6 - 1.0 mmol/g 100g
H 500560 30 Hydroxytrityl Polystyrene 500 - 560 µm 0.6 - 1.0 mmol/g 5g
H 500560 30 Hydroxytrityl Polystyrene 500 - 560 µm 0.6 - 1.0 mmol/g 25g
H 500560 30 Hydroxytrityl Polystyrene 500 - 560 µm 0.6 - 1.0 mmol/g 100g
B7.5.5.4 Trityl Linker on Polar PEG Spacer Resins
B7.5.5.4.1 HypoGel® Resins with Trityl Linker
HypoGel® is a hydrophilic gel type resin which combines high capacities with good solvent compatibility. Glycol spacers with n = 5 or 10 EO units separate the reactive sites from the polystyrene matrix and modify the hydrophobic properties of the polystyrene backbone. The hydrophilicity is between polystyrene and TentaGel® . Due to the spacer effect the functional group shows a higher mobility which results in higher kinetic rates and high resolution NMR spectra from immobilized compounds on the bead. The resin is compatible to a wide range of solvents and in contrast to polystyrene even polar solvents like methanol or ethanol can be used.
HypoGel® is a registered Trademark of Rapp Polymere GmbH
Literature: L 17
This very acid sensitive linker is useful for the immobilization of alcohols, amines and carboxylic acids. Before use, the trityl alcohol must be converted to the trityl chloride by treatment with acetyl chloride in DCM. The sensitivity towards acids is very comparable to the 2-chlorotrityl linker. Cleavage is in general achieved by using either 5 - 50 % TFA in CH?Cl? (containing 5 % triisopropylsilane) or acetic acid.
This resin can also be used in Fmoc peptide synthesis. Carboxylic acids can be released under very mild acidic conditions by treatment with AcOH/TFE/DCM or HFIP in DCM. Completely protected peptides are generated under this conditions.
Residues which are sensitive to racemisation during esterification reactions like His and Cys can be attached to the resin without racemisation. Due to the bulkiness of the trityl group, diketopiperazine formation is suppressed which make this linker ideal for peptides with C-terminal Pro.
货号 名称 particle size capacity 包装
SP200 110150 120 HypoGel® 200 TRT-OH 110 - 150 µm 0.6 - 0.8 mmol/g 5g
SP200 110150 120 HypoGel® 200 TRT-OH 110 - 150 µm 0.6 - 0.8 mmol/g 25g
SP200 110150 120 HypoGel® 200 TRT-OH 110 - 150 µm 0.6 - 0.8 mmol/g 100g
SP400 110150 120 HypoGel® 400 TRT-OH 110 - 150 µm 0.4 - 0.6 mmol/g 5g
SP400 110150 120 HypoGel® 400 TRT-OH 110 - 150 µm 0.4 - 0.6 mmol/g 25g
SP400 110150 120 HypoGel® 400 TRT-OH 110 - 150 µm 0.4 - 0.6 mmol/g 100g
B7.5.5.4.2 TentaGel® Resins with Trityl Linker
TentaGel® resins are grafted copolymers consisting of a low crosslinked polystyrene matrix on which polyethylene glycol (PEG or POE) is grafted. The PEG spacer is attached to the matrix via an ethyl ether group which increases stability towards acid treatment and minimizes PEG-leaching. As PEG is a "chameleon type" polymer with hydrophobic and hydrophilic properties, the graft copolymer shows modified physico chemical properties which are highly dominated by the PEG moiety (and no longer by the polystyrene matrix). These graft copolymers are pressure stable and can be used in batch processes as well as under continuous flow conditions. The PEG spacer is in the range of MW 3000 Da.
This highly acid sensitive linker is useful for the immobilization of alcohols, amines and carboxylic acids. Before use, the trityl alcohol must be converted to the trityl chloride by treatment with acetyl chloride in DCM. The sensitivity towards acids is very comparable to the 2-chlorotrityl linker. Cleavage is in general achieved by using either 5 - 50 % TFA in CH?Cl? (containing 5 % triisopropylsilane) or acetic acid.
This resin can also be used in Fmoc peptide synthesis. Carboxylic acids can be released under very mild acidic conditions by treatment with AcOH/TFE/DCM or HFIP in DCM. Completely protected peptides are generated under this conditions.
Residues which are sensitive to racemisation during esterification reactions like His and Cys can be attached to the resin without racemisation. Due to the bulkiness of the trityl group, diketopiperazine formation is suppressed which makes this linker ideal for peptides with C-terminal Pro.
Literature
L 4, L 5, L 6, L 7, L 24, L 25; see also: General Information
B7.5.5.4.2.1 TentaGel® HL TRT High Loaded TentaGel Resins with Hydroxytrityl Linker
This high loaded version of TentaGel® combines a significantly higher capacity with the advantages of
TentaGel® resins. The spacer is in the range of MW 1500 - 2000 Da.
货号 名称 particle size capacity 包装
HL12 012 TentaGel® HL TRT-OH 75 µm 0.3 - 0.4 mmol/g 1g
HL12 012 TentaGel® HL TRT-OH 75 µm 0.3 - 0.4 mmol/g 5g
HL12 012 TentaGel® HL TRT-OH 75 µm 0.3 - 0.4 mmol/g 25g
HL12 012 TentaGel® HL TRT-OH 75 µm 0.3 - 0.4 mmol/g 50g
B7.5.5.4.2.2 TentaGel® MB TRT TentaGel Macrobead Resins with Hydroxytrityl Linker
TentaGel® Macrobeads are highlighted by extraordinary large particle diameters and high capacities based on the TentaGel® technology and designed for single bead synthesis and single bead analysis.
货号 名称 particle size capacity 包装
MB 160 120 TentaGel® MB TRT-OH 140 - 170 µm 0.4 - 0.5 mmol/g 1g
MB 160 120 TentaGel® MB TRT-OH 140 - 170 µm 0.4 - 0.5 mmol/g 5g
MB 160 120 TentaGel® MB TRT-OH 140 - 170 µm 0.4 - 0.5 mmol/g 25g
MB 160 120 TentaGel® MB TRT-OH 140 - 170 µm 0.4 - 0.5 mmol/g 50g
MB 250 120 TentaGel® MB TRT-OH 200 - 250 µm 0.2 - 0.3 mmol/g 1g
MB 250 120 TentaGel® MB TRT-OH 200 - 250 µm 0.2 - 0.3 mmol/g 5g
MB 250 120 TentaGel® MB TRT-OH 200 - 250 µm 0.2 - 0.3 mmol/g 25g
MB 250 120 TentaGel® MB TRT-OH 200 - 250 µm 0.2 - 0.3 mmol/g 50g
MB 300 120 TentaGel® MB TRT-OH 280 - 320 µm 0.2 - 0.3 mmol/g 1g
MB 300 120 TentaGel® MB TRT-OH 280 - 320 µm 0.2 - 0.3 mmol/g 5g
MB 300 120 TentaGel® MB TRT-OH 280 - 320 µm 0.2 - 0.3 mmol/g 25g
MB 300 120 TentaGel® MB TRT-OH 280 - 320 µm 0.2 - 0.3 mmol/g 50g
B7.5.5.4.2.3 TentaGel® R TRT Cl TentaGel Research Resins with Chlorotrityl Linker
TentaGel® R TRT Cl TentaGel Research Resins with Chlorotrityl Linker
This preactivated resin is ready for loading with nucleophilic compounds and amino acids under basic conditions. Due to the hygroscopic nature of TentaGel resins, the resin should be used immediately.
A special designed resin for research synthesis. This resin is recommended for long peptide sequences (up to 100 residues) and difficult sequences. The resin shows an increased swelling volume and a significant lower loading.
This highly acid sensitive linker is useful for the immobilization of alcohols, amines and carboxylic acids. The sensitivity towards acids is very comparable to the 2-chlorotrityl linker. Cleavage is in general achieved by using either 5 - 50 % TFA in CH?Cl? (containing 5 % triisopropylsilane) or acetic acid.
This resin can also be used in Fmoc peptide synthesis. Carboxylic acids can be released under very mild acidic conditions by treatment with AcOH/TFE/DCM or HFIP in DCM. Completely protected peptides are generated under this conditions. The sensitivity toward acid treatment is comparable to the 2-CTC linker.
Residues which are sensitive to racemisation during esterification reactions like His and Cys can be attached to the resin without racemisation. Due to the bulkiness of the trityl group, diketopiperazine formation is suppressed which make this linker ideal for peptides with C-terminal Pro.
货号 名称 particle size capacity 包装
R 28 031 TentaGel® R TRT-Cl 90 µm 0.15 - 0.22 mmol/g 5g
R 28 031 TentaGel® R TRT-Cl 90 µm 0.15 - 0.22 mmol/g 25g
R 28 031 TentaGel® R TRT-Cl 90 µm 0.15 - 0.22 mmol/g 50g
B7.5.5.4.2.4 TentaGel® S TRT Standard TentaGel Resins with Hydroxytrityl Linker
Standard resin for a large number of applications, useful in batch and flow through systems.
货号 名称 particle size capacity 包装
S 30 012 TentaGel® S TRT-OH 90 µm 0.2 - 0.28 mmol/g 1g
S 30 012 TentaGel® S TRT-OH 90 µm 0.2 - 0.28 mmol/g 5g
S 30 012 TentaGel® S TRT-OH 90 µm 0.2 - 0.28 mmol/g 25g
S 30 012 TentaGel® S TRT-OH 90 µm 0.2 - 0.28 mmol/g 50g
B7.5.5.4.2.5 TentaGel® S TRT Cl Standard TentaGel Resins with Chlorotrityl Linker
TentaGel® S TRT Cl Standard TentaGel Resins with Chlorotrityl Linker
This preactivated resin is ready for loading with nucleophilic compounds and amino acids under basic conditions. Due to the hygroscopic nature of TentaGel resins, the resin should be used immediately.
Standard resin for a large number of applications, useful in batch and flow through systems.
This resin is recommended for synthesis of standard peptides up to 40 residues in length.
This highly acid sensitive linker is useful for the immobilization of alcohols, amines and carboxylic acids. The sensitivity towards acids is very comparable to the 2-chlorotrityl linker. Cleavage is in general achieved by using either 5 - 50 % TFA in CH?Cl? (containing 5 % triisopropylsilane) or acetic acid.
This resin can also be used in Fmoc peptide synthesis. Carboxylic acids can be released under very mild acidic conditions by treatment with AcOH/TFE/DCM or HFIP in DCM. Completely protected peptides are generated under this conditions.
Residues which are sensitive to racemisation during esterification reactions like His and Cys can be attached to the resin without racemisation. Due to the bulkiness of the trityl group, diketopiperazine formation is suppressed which makes this linker ideal for peptides with C-terminal Pro.
Literature
L 14
货号 名称 particle size capacity 包装
S 30 031 TentaGel® S TRT-Cl 90 µm 0.2 - 0.3 mmol/g 5g
S 30 031 TentaGel® S TRT-Cl 90 µm 0.2 - 0.3 mmol/g 25g
S 30 031 TentaGel® S TRT-Cl 90 µm 0.2 - 0.3 mmol/g 50g

B7.6 Resins with Aromatic Formyl Linkers

B7.6.1 Polar PEG Spacer Resins with Aromatic Formyl Linker
B7.6.1.1 4-Formyl Phenoxy on HypoGel Resins ( FP-linker)
4-Formyl Phenoxy on HypoGel Resins ( FP-linker)
HypoGel® is a hydrophilic gel type resin which combines high capacities with good solvent compatibility. Glycol spacers with n = 5 or 10 EO units separate the reactive sites from the polystyrene matrix and modify the hydrophobic properties of the polystyrene backbone. Due to the spacer effect the functional group shows a higher mobility which results in higher kinetic rates and high resolution NMR spectra from immobilized compounds on the bead. The resin is compatible to a wide range of solvents and in contrast to polystyrene even polar solvents like methanol or ethanol can be used.
These resins show high loading and a hydrophilicity between polystyrene and TentaGel®
L 30, L 31
 
Due to the lack of amide bonds and of benzylic linkages as well as the very good swelling properties in a broad variety of solvents this resin is well suited for solid phase syntheses of secondary sulfonamides and carboxamides.
Literature
L17
货号 名称 particle size capacity 包装
SP200 110150 170 HypoGel® 200 FP 110 - 150 µm 0.5 - 0.7 mmol/g 5g
SP200 110150 170 HypoGel® 200 FP 110 - 150 µm 0.5 - 0.7 mmol/g 25g
SP200 110150 170 HypoGel® 200 FP 110 - 150 µm 0.5 - 0.7 mmol/g 100g
SP400 110150 170 HypoGel® 400 FP 110 - 150 µm 0.4 - 0.6 mmol/g 5g
SP400 110150 170 HypoGel® 400 FP 110 - 150 µm 0.4 - 0.6 mmol/g 25g
SP400 110150 170 HypoGel® 400 FP 110 - 150 µm 0.4 - 0.6 mmol/g 100g
B7.6.1.2 4-Formyl-3-Methoxy Phenoxy on HypoGel Resins ( FMP-linker)
货号 名称 particle size capacity 包装
SP200 110150 160 HypoGel® 200 FMP 110 - 150 µm 0.5 - 0.7 mmol/g 5g
SP200 110150 160 HypoGel® 200 FMP 110 - 150 µm 0.5 - 0.7 mmol/g 25g
SP200 110150 160 HypoGel® 200 FMP 110 - 150 µm 0.5 - 0.7 mmol/g 100g
SP400 110150 160 HypoGel® 400 FMP 110 - 150 µm 0.4 - 0.6 mmol/g 5g
SP400 110150 160 HypoGel® 400 FMP 110 - 150 µm 0.4 - 0.6 mmol/g 25g
SP400 110150 160 HypoGel® 400 FMP 110 - 150 µm 0.4 - 0.6 mmol/g 100g
B7.6.1.3 4-Formyl-3-Methoxy Phenoxy on TentaGel Resins ( FMP-linker)
4-Formyl-3-Methoxy Phenoxy on TentaGel Resins ( FMP-linker)
TentaGel® resins are grafted copolymers consisting of a low crosslinked polystyrene matrix on which polyethylene glycol (PEG or POE) is grafted. The PEG spacer is attached to the matrix via an ethyl ether group which increases stability towards acid treatment and minimizes PEG-leaching. As PEG is a "chameleon type" polymer with hydrophobic and hydrophilic properties, the graft copolymer shows modified physico chemical properties which are highly dominated by the PEG moiety (and no longer by the polystyrene matrix). These graft copolymers are pressure stable and can be used in batch processes as well as under continuous flow conditions. The PEG spacer is in the range of MW 3000 Da.
Due to the lack of amide bonds and of benzylic linkages as well as the excellent swelling properties in a great variety of solvents this resin is ideal for solid phase syntheses of secondary sulfonamides and carboxamides.
Literature
L 4, L 5, L 6, L 7, L 24, L 25, L 31; see also: General Information
B7.6.1.3.1 TentaGel® HL FMP High Loaded TentaGel Resins Modified with FMP Linker
This highloaded version of TentaGel® combines a significantly higher capacity with the advantages of TentaGel® resins. The spacer is in the range of MW 1500 - 2000 Da.
货号 名称 particle size capacity 包装
HL 12 016 TentaGel® HL FMP 75 µm 0.3 - 0.4 mmol/g 1g
HL 12 016 TentaGel® HL FMP 75 µm 0.3 - 0.4 mmol/g 5g
HL 12 016 TentaGel® HL FMP 75 µm 0.3 - 0.4 mmol/g 25g
HL 12 016 TentaGel® HL FMP 75 µm 0.3 - 0.4 mmol/g 100g
B7.6.1.3.2 TentaGel® MB FMP TentaGel Macrobeads Modified with FMP Linker
货号 名称 particle size capacity 包装
MB 160 160 TentaGel® MB FMP 140 - 170 µm 0.35 - 0.45 1g
MB 160 160 TentaGel® MB FMP 140 - 170 µm 0.35 - 0.45 5g
MB 160 160 TentaGel® MB FMP 140 - 170 µm 0.35 - 0.45 25g
MB 160 160 TentaGel® MB FMP 140 - 170 µm 0.35 - 0.45 100g
MB 250 160 TentaGel® MB FMP 200 - 250 µm 0.2 - 0.3 1g
MB 250 160 TentaGel® MB FMP 200 - 250 µm 0.2 - 0.3 5g
MB 250 160 TentaGel® MB FMP 200 - 250 µm 0.2 - 0.3 25g
MB 250 160 TentaGel® MB FMP 200 - 250 µm 0.2 - 0.3 100g
MB 300 160 TentaGel® MB FMP 280 - 320 µm 0.2 - 0.3 1g
MB 300 160 TentaGel® MB FMP 280 - 320 µm 0.2 - 0.3 5g
MB 300 160 TentaGel® MB FMP 280 - 320 µm 0.2 - 0.3 25g
MB 300 160 TentaGel® MB FMP 280 - 320 µm 0.2 - 0.3 100g
B7.6.1.3.3 TentaGel® S FMP Standard TentaGel Resins Modified with FMP Linker
货号 名称 particle size capacity 包装
S 30 016 TentaGel® S FMP 90 µm 0.2 - 0.25 1g
S 30 016 TentaGel® S FMP 90 µm 0.2 - 0.25 5g
S 30 016 TentaGel® S FMP 90 µm 0.2 - 0.25 25g
S 30 016 TentaGel® S FMP 90 µm 0.2 - 0.25 100g
B7.6.2 Polystyrene based Resins
B7.6.2.1 4-Formyl Phenoxyethyl Polystyrene Resins (FP-Linker, 4-Alkoxybenzaldehyd resin)
货号 名称 particle size capacity 包装
HA 1 100 07 Polystyrene A FP 100 - 200 mesh 0.7 - 1.1 mmol/g 5g
HA 1 100 07 Polystyrene A FP 100 - 200 mesh 0.7 - 1.1 mmol/g 25g
HA 1 100 07 Polystyrene A FP 100 - 200 mesh 0.7 - 1.1 mmol/g 100g
HA 1 400 07 Polystyrene A FP 200 - 400 mesh 0.7 - 1.1 mmol/g 5g
HA 1 400 07 Polystyrene A FP 200 - 400 mesh 0.7 - 1.1 mmol/g 25g
HA 1 400 07 Polystyrene A FP 200 - 400 mesh 0.7 - 1.1 mmol/g 100g
HA 125160 07 Polystyrene A FP 125 - 160 µm 0.7 - 1.1 mmol/g 5g
HA 125160 07 Polystyrene A FP 125 - 160 µm 0.7 - 1.1 mmol/g 25g
HA 125160 07 Polystyrene A FP 125 - 160 µm 0.7 - 1.1 mmol/g 100g
HA 160200 07 Polystyrene A FP 160 - 200 µm 0.7 - 1.1 mmol/g 5g
HA 160200 07 Polystyrene A FP 160 - 200 µm 0.7 - 1.1 mmol/g 25g
HA 160200 07 Polystyrene A FP 160 - 200 µm 0.7 - 1.1 mmol/g 100g
HA 250315 07 Polystyrene A FP 250 - 315 µm 0.5 - 0.8 mmol/g 5g
HA 250315 07 Polystyrene A FP 250 - 315 µm 0.5 - 0.8 mmol/g 25g
HA 250315 07 Polystyrene A FP 250 - 315 µm 0.5 - 0.8 mmol/g 100g
HA 400450 07 Polystyrene A FP 400 - 450 µm 0.5 - 0.8 mmol/g 5g
HA 400450 07 Polystyrene A FP 400 - 450 µm 0.5 - 0.8 mmol/g 25g
HA 400450 07 Polystyrene A FP 400 - 450 µm 0.5 - 0.8 mmol/g 100g
HA 500560 07 Polystyrene A FP 500 - 560 µm 0.5 - 0.8 mmol/g 5g
HA 500560 07 Polystyrene A FP 500 - 560 µm 0.5 - 0.8 mmol/g 25g
HA 500560 07 Polystyrene A FP 500 - 560 µm 0.5 - 0.8 mmol/g 100g
B7.6.2.2 4-Formyl-3-Methoxy Phenoxybutyl Polystyrene Resins (FMP-Linker)
货号 名称 particle size capacity 包装
HB 045080 08 Polystyrene C4 FMP 45 - 80 µm 0.7 - 1.0 mmol/g 5g
HB 045080 08 Polystyrene C4 FMP 45 - 80 µm 0.7 - 1.0 mmol/g 25g
HB 045080 08 Polystyrene C4 FMP 45 - 80 µm 0.7 - 1.0 mmol/g 100g
HB 080160 08 Polystyrene C4 FMP 80 - 160 µm 0.7 - 1.0 mmol/g 5g
HB 080160 08 Polystyrene C4 FMP 80 - 160 µm 0.7 - 1.0 mmol/g 25g
HB 080160 08 Polystyrene C4 FMP 80 - 160 µm 0.7 - 1.0 mmol/g 100g
HB 125160 08 Polystyrene C4 FMP 125 - 160 µm 0.7 - 1.0 mmol/g 5g
HB 125160 08 Polystyrene C4 FMP 125 - 160 µm 0.7 - 1.0 mmol/g 25g
HB 125160 08 Polystyrene C4 FMP 125 - 160 µm 0.7 - 1.0 mmol/g 100g
B7.6.2.3 4-Formyl-3-Methoxy Phenoxyethyl Polystyrene Resins (FMP-Linker)
货号 名称 particle size capacity 包装
HA 1 100 08 Polystyrene A FMP 100 - 200 mesh 0.7 - 1.1 mmol/g 5g
HA 1 100 08 Polystyrene A FMP 100 - 200 mesh 0.7 - 1.1 mmol/g 25g
HA 1 100 08 Polystyrene A FMP 100 - 200 mesh 0.7 - 1.1 mmol/g 100g
HA 1 400 08 Polystyrene A FMP 200 - 400 mesh 0.7 - 1.1 mmol/g 5g
HA 1 400 08 Polystyrene A FMP 200 - 400 mesh 0.7 - 1.1 mmol/g 25g
HA 1 400 08 Polystyrene A FMP 200 - 400 mesh 0.7 - 1.1 mmol/g 100g
HA 125160 08 Polystyrene A FMP 125 - 160 µm 0.7 - 1.1 mmol/g 5g
HA 125160 08 Polystyrene A FMP 125 - 160 µm 0.7 - 1.1 mmol/g 25g
HA 125160 08 Polystyrene A FMP 125 - 160 µm 0.7 - 1.1 mmol/g 100g
HA 160200 08 Polystyrene A FMP 160 - 200 µm 0.7 - 1.1 mmol/g 5g
HA 160200 08 Polystyrene A FMP 160 - 200 µm 0.7 - 1.1 mmol/g 25g
HA 160200 08 Polystyrene A FMP 160 - 200 µm 0.7 - 1.1 mmol/g 100g
HA 250315 08 Polystyrene A FMP 250 - 315 µm 0.5 - 0.8 mmol/g 5g
HA 250315 08 Polystyrene A FMP 250 - 315 µm 0.5 - 0.8 mmol/g 25g
HA 250315 08 Polystyrene A FMP 250 - 315 µm 0.5 - 0.8 mmol/g 100g
HA 400450 08 Polystyrene A FMP 400 - 450 µm 0.5 - 0.8 mmol/g 5g
HA 400450 08 Polystyrene A FMP 400 - 450 µm 0.5 - 0.8 mmol/g 25g
HA 400450 08 Polystyrene A FMP 400 - 450 µm 0.5 - 0.8 mmol/g 100g
HA 500560 08 Polystyrene A FMP 500 - 560 µm 0.5 - 0.8 mmol/g 5g
HA 500560 08 Polystyrene A FMP 500 - 560 µm 0.5 - 0.8 mmol/g 25g
HA 500560 08 Polystyrene A FMP 500 - 560 µm 0.5 - 0.8 mmol/g 100g

B7.7 Resins with Base Labile Linkers

B7.7.1 Polar PEG Spacer Resins with Base Labile Linkers
B7.7.1.1 4-(Hydroxymethyl) Benzoic Acid (HMBA) on HypoGel® Resins
HypoGel® is a hydrophilic gel type resin which combines high capacities with good solvent compatibility. Glycol spacers with n = 5 or 10 EO units separate the reactive sites from the polystyrene matrix and modify the hydrophobic properties of the polystyrene backbone. Due to the spacer effect the functional group shows a higher mobility which results in higher kinetic rates and high resolution NMR spectra from immobilized compounds on the bead. The resin is compatible to a wide range of solvents and in contrast to polystyrene even polar solvents like methanol or ethanol can be used.
These resins show high loading and a hydrophilicity between polystyrene and TentaGel®
This resin is derived from HypoGel® amine and the base labile 4-(hydroxymethyl)benzoic acid linker. It is a versatile support for the immobilization of carboxylic acids. The resulting ester bond is stable to strong acids but is cleaved by nucleophiles like amines, hydrazine or alkoxides.
Literature
L 17
货号 名称 particle size capacity 包装
SP200 110150 140 HypoGel® 200 HMBA 110 - 150 µm 0.6 - 0.8 mmol/g 5g
SP200 110150 140 HypoGel® 200 HMBA 110 - 150 µm 0.6 - 0.8 mmol/g 25g
SP200 110150 140 HypoGel® 200 HMBA 110 - 150 µm 0.6 - 0.8 mmol/g 100g
SP400 110150 140 HypoGel® 400 HMBA 110 - 150 µm 0.4 - 0.6 mmol/g 5g
SP400 110150 140 HypoGel® 400 HMBA 110 - 150 µm 0.4 - 0.6 mmol/g 25g
SP400 110150 140 HypoGel® 400 HMBA 110 - 150 µm 0.4 - 0.6 mmol/g 100g
B7.7.1.2 4-(Hydroxymethyl) Benzoic Acid (HMBA) on TentaGel® Resins
B7.7.1.2.1 TentaGel® HL HMBA HMBA Linker Attached to High Loaded TentaGel Resins
货号 名称 particle size capacity 包装
HL12 014 TentaGel® HL HMBA 75 µm 0.3 - 0.4 mmol/g 1g
HL12 014 TentaGel® HL HMBA 75 µm 0.3 - 0.4 mmol/g 5g
HL12 014 TentaGel® HL HMBA 75 µm 0.3 - 0.4 mmol/g 25g
HL12 014 TentaGel® HL HMBA 75 µm 0.3 - 0.4 mmol/g 50g
B7.7.1.2.2 TentaGel® MB HMBA HMBA Linker Attached to TentaGel Macrobeads
货号 名称 particle size capacity 包装
MB 160 140 TentaGel® MB HMBA 140 - 170 µm 0.4 - 0.5 mmol/g 1g
MB 160 140 TentaGel® MB HMBA 140 - 170 µm 0.4 - 0.5 mmol/g 5g
MB 160 140 TentaGel® MB HMBA 140 - 170 µm 0.4 - 0.5 mmol/g 25g
MB 160 140 TentaGel® MB HMBA 140 - 170 µm 0.4 - 0.5 mmol/g 50g
MB 250 140 TentaGel® MB HMBA 200 - 250 µm 0.2 - 0.3 mmol/g 1g
MB 250 140 TentaGel® MB HMBA 200 - 250 µm 0.2 - 0.3 mmol/g 5g
MB 250 140 TentaGel® MB HMBA 200 - 250 µm 0.2 - 0.3 mmol/g 25g
MB 250 140 TentaGel® MB HMBA 200 - 250 µm 0.2 - 0.3 mmol/g 50g
MB 300 140 TentaGel® MB HMBA 280 - 320 µm 0.2 - 0.3 mmol/g 1g
MB 300 140 TentaGel® MB HMBA 280 - 320 µm 0.2 - 0.3 mmol/g 5g
MB 300 140 TentaGel® MB HMBA 280 - 320 µm 0.2 - 0.3 mmol/g 25g
MB 300 140 TentaGel® MB HMBA 280 - 320 µm 0.2 - 0.3 mmol/g 50g
B7.7.1.2.3 TentaGel® R HMBA HMBA Linker Attached to TentaGel Research Resins
货号 名称 particle size capacity 包装
R 28 023 TentaGel® R HMBA 90 µm 0.18 - 0.22 mmol/g 1g
R 28 023 TentaGel® R HMBA 90 µm 0.18 - 0.22 mmol/g 5g
R 28 023 TentaGel® R HMBA 90 µm 0.18 - 0.22 mmol/g 25g
R 28 023 TentaGel® R HMBA 90 µm 0.18 - 0.22 mmol/g 50g
B7.7.1.2.4 TentaGel® S HMBA HMBA Linker Attached to Standard TentaGel Resins
货号 名称 particle size capacity 包装
S 30 014 TentaGel® S HMBA 90 µm 0.2 - 0.28 mmol/g 1g
S 30 014 TentaGel® S HMBA 90 µm 0.2 - 0.28 mmol/g 5g
S 30 014 TentaGel® S HMBA 90 µm 0.2 - 0.28 mmol/g 25g
S 30 014 TentaGel® S HMBA 90 µm 0.2 - 0.28 mmol/g 50g
B7.7.2 Polystyrene Resins with Base Labile Linkers
B7.7.2.1 4-(Hydroxymethyl) Benzoic Acid (HMBA) on Aminoethyl Polystyrene
货号 名称 particle size capacity 包装
HA 1 100 14 Polystyrene A HMBA 100 - 200 mesh 0.8 - 1.2 mmol/g 5g
HA 1 100 14 Polystyrene A HMBA 100 - 200 mesh 0.8 - 1.2 mmol/g 25g
HA 1 100 14 Polystyrene A HMBA 100 - 200 mesh 0.8 - 1.2 mmol/g 100g
HA 1 400 14 Polystyrene A HMBA 200 - 400 mesh 0.8 - 1.2 mmol/g 5g
HA 1 400 14 Polystyrene A HMBA 200 - 400 mesh 0.8 - 1.2 mmol/g 25g
HA 1 400 14 Polystyrene A HMBA 200 - 400 mesh 0.8 - 1.2 mmol/g 100g
HA 125160 14 Polystyrene A HMBA 125 - 160 µm 0.8 - 1.2 mmol/g 5g
HA 125160 14 Polystyrene A HMBA 125 - 160 µm 0.8 - 1.2 mmol/g 25g
HA 125160 14 Polystyrene A HMBA 125 - 160 µm 0.8 - 1.2 mmol/g 100g
HA 160200 14 Polystyrene A HMBA 160 - 200 µm 0.8 - 1.2 mmol/g 5g
HA 160200 14 Polystyrene A HMBA 160 - 200 µm 0.8 - 1.2 mmol/g 25g
HA 160200 14 Polystyrene A HMBA 160 - 200 µm 0.8 - 1.2 mmol/g 100g
HA 250315 14 Polystyrene A HMBA 250 - 315 µm 0.6 - 1.0 mmol/g 5g
HA 250315 14 Polystyrene A HMBA 250 - 315 µm 0.6 - 1.0 mmol/g 25g
HA 250315 14 Polystyrene A HMBA 250 - 315 µm 0.6 - 1.0 mmol/g 100g
HA 400450 14 Polystyrene A HMBA 400 - 450 µm 0.6 - 1.0 mmol/g 5g
HA 400450 14 Polystyrene A HMBA 400 - 450 µm 0.6 - 1.0 mmol/g 25g
HA 400450 14 Polystyrene A HMBA 400 - 450 µm 0.6 - 1.0 mmol/g 100g
HA 500560 14 Polystyrene A HMBA 500 - 560 µm 0.6 - 1.0 mmol/g 5g
HA 500560 14 Polystyrene A HMBA 500 - 560 µm 0.6 - 1.0 mmol/g 25g
HA 500560 14 Polystyrene A HMBA 500 - 560 µm 0.6 - 1.0 mmol/g 100g
B7.7.2.2 4-(Hydroxymethyl) Benzoic Acid (HMBA) on Aminomethyl Polystyrene
货号 名称 particle size capacity 包装
H 1 100 14 Polystyrene AM HMBA 100 - 200 mesh 0.8 - 1.2 mmol/g 5g
H 1 100 14 Polystyrene AM HMBA 100 - 200 mesh 0.8 - 1.2 mmol/g 25g
H 1 100 14 Polystyrene AM HMBA 100 - 200 mesh 0.8 - 1.2 mmol/g 100g
H 1 400 14 Polystyrene AM HMBA 200 - 400 mesh 0.8 - 1.2 mmol/g 5g
H 1 400 14 Polystyrene AM HMBA 200 - 400 mesh 0.8 - 1.2 mmol/g 25g
H 1 400 14 Polystyrene AM HMBA 200 - 400 mesh 0.8 - 1.2 mmol/g 100g
H 125160 14 Polystyrene AM HMBA 125 - 160 µm 0.8 - 1.2 mmol/g 5g
H 125160 14 Polystyrene AM HMBA 125 - 160 µm 0.8 - 1.2 mmol/g 25g
H 125160 14 Polystyrene AM HMBA 125 - 160 µm 0.8 - 1.2 mmol/g 100g
H 160200 14 Polystyrene AM HMBA 160 - 200 µm 0.8 - 1.2 mmol/g 5g
H 160200 14 Polystyrene AM HMBA 160 - 200 µm 0.8 - 1.2 mmol/g 25g
H 160200 14 Polystyrene AM HMBA 160 - 200 µm 0.8 - 1.2 mmol/g 100g
H 250315 14 Polystyrene AM HMBA 250 - 315 µm 0.6 - 1.0 mmol/g 5g
H 250315 14 Polystyrene AM HMBA 250 - 315 µm 0.6 - 1.0 mmol/g 25g
H 250315 14 Polystyrene AM HMBA 250 - 315 µm 0.6 - 1.0 mmol/g 100g
H 400450 14 Polystyrene AM HMBA 400 - 450 µm 0.6 - 1.0 mmol/g 5g
H 400450 14 Polystyrene AM HMBA 400 - 450 µm 0.6 - 1.0 mmol/g 25g
H 400450 14 Polystyrene AM HMBA 400 - 450 µm 0.6 - 1.0 mmol/g 100g
H 500560 14 Polystyrene AM HMBA 500 - 560 µm 0.6 - 1.0 mmol/g 5g
H 500560 14 Polystyrene AM HMBA 500 - 560 µm 0.6 - 1.0 mmol/g 25g
H 500560 14 Polystyrene AM HMBA 500 - 560 µm 0.6 - 1.0 mmol/g 100g

²B8 Scavenger Resins and Polymer Bound Reagents

B8.1 Polymer Supported Protecting Groups

B8.1.1 Bromo Acetal Resins
B8.1.1.1 Bromoacetal Linker on HypoGel® Resins
货号 名称 particle size capacity 包装
SP200 110150 190 HypoGel® 200 Bromo Acetal 110 - 150 µm 0.75 - 0.95 mmol/g 5g
SP200 110150 190 HypoGel® 200 Bromo Acetal 110 - 150 µm 0.75 - 0.95 mmol/g 25g
SP200 110150 190 HypoGel® 200 Bromo Acetal 110 - 150 µm 0.75 - 0.95 mmol/g 100g
SP400 110150 190 HypoGel® 400 Bromo Acetal 110 - 150 µm 0.6 - 0.8 mmol/g 5g
SP400 110150 190 HypoGel® 400 Bromo Acetal 110 - 150 µm 0.6 - 0.8 mmol/g 25g
SP400 110150 190 HypoGel® 400 Bromo Acetal 110 - 150 µm 0.6 - 0.8 mmol/g 100g
B8.1.1.2 Bromoacetal Linker on TentaGel® Resins
货号 名称 particle size capacity 包装
HL 12 019 TentaGel® HL Bromo Acetal 75 µm 0.4 - 0.55 mmol/g 5g
HL 12 019 TentaGel® HL Bromo Acetal 75 µm 0.4 - 0.55 mmol/g 25g
HL 12 019 TentaGel® HL Bromo Acetal 75 µm 0.4 - 0.55 mmol/g 100g
B8.1.2 Diol Resins
B8.1.2.1 HypoGel® Diol
货号 名称 particle size capacity 包装
SP200 110150 10 HypoGel® 200 Diol 110 - 150 µm 1.2 - 1.5 mmol/g 5g
SP200 110150 10 HypoGel® 200 Diol 110 - 150 µm 1.2 - 1.5 mmol/g 25g
SP200 110150 10 HypoGel® 200 Diol 110 - 150 µm 1.2 - 1.5 mmol/g 100g
SP400 110150 10 HypoGel® 400 Diol 110 - 150 µm 0.9 - 1.3 mmol/g 5g
SP400 110150 10 HypoGel® 400 Diol 110 - 150 µm 0.9 - 1.3 mmol/g 25g
SP400 110150 10 HypoGel® 400 Diol 110 - 150 µm 0.9 - 1.3 mmol/g 100g
B8.1.2.2 TentaGel® Diol
货号 名称 particle size capacity 包装
HL 12 01 TentaGel® HL Diol 75 µm 0.6 - 0.8 mmol/g 5g
HL 12 01 TentaGel® HL Diol 75 µm 0.6 - 0.8 mmol/g 25g
HL 12 01 TentaGel® HL Diol 75 µm 0.6 - 0.8 mmol/g 100g

B8.2 Scavenger Resins - ScavengePore®

货号 名称 capacity 包装
SC11011 ScavengePore® Benzenesulfonic acid, Na+-form 1 - 2 mmol/g 10g
SC11011 ScavengePore® Benzenesulfonic acid, Na+-form 1 - 2 mmol/g 100g
SC11012 ScavengePore® Benzyltriethylammonium chloride 0.5 - 1 mmol/g 10g
SC11012 ScavengePore® Benzyltriethylammonium chloride 0.5 - 1 mmol/g 100g
SC11013 ScavengePore® Benzoic Acid 0.5 - 2.0 mmol/g 5g
SC11013 ScavengePore® Benzoic Acid 0.5 - 2.0 mmol/g 25g
SC11014 ScavengePore® Benzenesulfonic acid, H+-form 1 - 2 mmol/g 10g
SC11014 ScavengePore® Benzenesulfonic acid, H+-form 1 - 2 mmol/g 100g
SC11102 ScavengePore® Benzylamine 0.5 - 1.5 mmol/g and 2 - 3.5 mmol/g 5g
SC11102 ScavengePore® Benzylamine 0.5 - 1.5 mmol/g and 2 - 3.5 mmol/g 25g
SC11103 ScavengePore® Benzyl Isocyanate 0.5 - 1.1 mmol/g 5g
SC11103 ScavengePore® Benzyl Isocyanate 0.5 - 1.1 mmol/g 25g
SC11207 ScavengePore® 4-Phenethyloxybenzaldehyde 0.5 - 1.2 mmol/g 5g
SC11207 ScavengePore® 4-Phenethyloxybenzaldehyde 0.5 - 1.2 mmol/g 25g
SC11208 ScavengePore® Phenethyldiethylamine 0.5 - 1.5 mmol/g 5g
SC11208 ScavengePore® Phenethyldiethylamine 0.5 - 1.5 mmol/g 25g
SC11209 ScavengePore® Phenethylmorpholine 0.5 - 1.2 mmol/g 5g
SC11209 ScavengePore® Phenethylmorpholine 0.5 - 1.2 mmol/g 25g
SC11210 ScavengePore® Phenethylpiperidine 0.5 - 1.2 mmol/g 5g
SC11210 ScavengePore® Phenethylpiperidine 0.5 - 1.2 mmol/g 25g

B8.3 Triphenylphosphine Resins

B8.3.1 Polymer Supported Palladium
货号 名称 capacity 包装
HR 100 31-Pd Polystyrene-Tetrakis (Triphenylphosphine) Palladium 100 - 200 mesh 1g
HR 100 31-Pd Polystyrene-Tetrakis (Triphenylphosphine) Palladium 100 - 200 mesh 5g
B8.3.2 Polystyrene Triphenylphosphine
货号 名称 particle size capacity 包装
HR 100 31-0 Polystyrene-Triphenylphosphine 100 - 200 mesh 1 - 1.5 mmol/g 5g
HR 100 31-0 Polystyrene-Triphenylphosphine 100 - 200 mesh 1 - 1.5 mmol/g 25g
HR 100 31-0 Polystyrene-Triphenylphosphine 100 - 200 mesh 1 - 1.5 mmol/g 100g
HR 400 31-0 Polystyrene-Triphenylphosphine 200 - 400 mesh 1 - 1.5 mmol/g 5g
HR 400 31-0 Polystyrene-Triphenylphosphine 200 - 400 mesh 1 - 1.5 mmol/g 25g
HR 400 31-0 Polystyrene-Triphenylphosphine 200 - 400 mesh 1 - 1.5 mmol/g 100g
 
 

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